Famotidine Ranigast 20 mg x 30 coated tablets

What is Famotidine Ranigast and what does it do?

Famotidine Ranigast is a drug used in peptic ulcer disease and in gastroesophageal reflux disease. The drug contains the active substance - famotidine in a dose of 20 mg, which belongs to the group of drugs called H2 receptor antagonists.

Famotidine inhibits the secretion of hydrochloric acid, also stimulated by food and pentagastrin, and reduces the concentration of pepsin in gastric juice.

The usual dose is 1 tablet once or a maximum of twice a day. The daily dose of the drug should not exceed 40 mg. The effect of Famotidine Ranigast tablets lasts for 10 to 12 hours.

What are the indications for the use of Famotidine Ranigast?

Short-term symptomatic treatment of stomach problems not related to an organic disease of the gastrointestinal tract, such as:

dyspepsia,

heartburn,

hyperacidity.

Active substance: Famotidinum

The active substance is famotidine. Each tablet contains 20 mg of famotidine.

The other ingredients are:

Tablet core: pregelatinized starch, powdered cellulose, magnesium stearate, talc.

Tablet coating: hypromellose, titanium dioxide, macrogol 6000, talc, cochineal red lake (E124).

How to dose Famotidine Ranigast tablets?

If symptoms occur, usually take 1 tablet of Famotidine Ranigast 20 mg per day.

If the symptoms recur, you can take 1 tablet of 20 mg twice a day.

The daily dose of Famotidine Ranigast should not exceed 40 mg (2 tablets).

The tablet should be swallowed whole with a small amount of water.

The medicine should not be used without consulting a doctor for longer than 2 weeks. If your symptoms do not improve after 2 weeks of treatment, seek medical advice immediately.

Always use this medicine exactly as described in the package leaflet or as instructed by your doctor or pharmacist. If you have any doubts, please contact your doctor or pharmacist again.

Use of the drug in children and adolescents

The drug should not be used in children and adolescents.

p>

When should you not take Famotidine Ranigast?

if you are allergic to famotidine or any of the other ingredients of this medicine;

if you are allergic to other antagonist medicines a history of H2 receptors;

if you suffer from kidney failure.

Contents:

Famotidine Ranigast pack contains 20 tablets and leaflet.

Storage method: below 25°C

Manufacturer / Responsible entity: POLPHARMA

Authorization: MZ 0147

Important before use

Warnings

Before you start taking Famotidine Ranigast, you should talk to your doctor or pharmacist:

if you have kidney problems.

Famotidine Ranigast may mask the symptoms of other diseases, including stomach cancer. Therefore, if any of the following conditions occur before or while taking the drug, you should contact your doctor immediately:

recurrent vomiting,

appearance of vomiting with food or blood ,

passing black stools (stools tinted with blood),

if you suffer from weight loss, difficulty swallowing or persistent abdominal pain along with indigestion,

if the patient has not previously had stomach problems (dyspeptic) or they have occurred but have recently changed - this applies especially to middle-aged or elderly people.

If the symptoms do not subside after 14 days of treatment, contact your doctor immediately to verify the diagnosis.

Famotidine Ranigast during pregnancy and breast-feeding

If you are pregnant or breast-feeding, think you may be pregnant or are planning to have a baby, ask your doctor or pharmacist for advice before taking this medicine.

Famotidine Ranigast should only be used in pregnant women if, in the opinion of your doctor, it is absolutely necessary.

Women breastfeeding women should stop taking Famotidine Ranigast or breast-feeding as famotidine passes into breast milk.

Driving

Side effects such as: dizziness, which may impair psychophysical performance. If you experience such side effects, do not drive or operate machinery.

Overdose

If you take more than the recommended dose, contact your doctor immediately. .

In the event of an overdose, your doctor will decide on symptomatic treatment, consisting of removing the unabsorbed drug from the gastrointestinal tract, monitoring the clinical condition and administering supportive treatment.

If you have any further doubts regarding the use this medicine, talk to your doctor or pharmacist.

Famotidine Ranigast and interactions with other medicines

Tell your doctor or pharmacist about all the medicines you are taking currently or recently, as well as about the drugs that the patient plans to use.

Famotidine does not interact with warfarin (a drug that reduces blood clotting), theophylline (a drug used to treat asthma and other respiratory diseases), phenytoin (anti-epileptic drug), diazepam (anxiolytic and sedative drug), propranolol (heart drug), aminophenazone, phenazone (painkillers).

Changes in the pH of gastric contents may affect the bioavailability of some drugs (e.g. reducing the absorption of atazanavir (an antiviral medicine used to treat HIV infection)).

Famotidine may reduce the absorption of ketoconazole and itraconazole (antifungal medicines). Ketoconazole should be administered two hours before famotidine.

Antacids may reduce the absorption of famotidine and lead to lower famotidine serum concentrations. Therefore, famotidine should be taken 1-2 hours before the administration of antacids.

The administration of probenecid (a medicine used to treat gout) may delay the excretion of famotidine. Concomitant administration of famotidine and probenecid should be avoided.

Concomitant administration of sucralfate (a protective agent used to treat peptic ulcer disease) should be avoided within two hours of administration of famotidine.

There is a risk of loss of effectiveness of calcium carbonate , used in dialysis patients as a medicine to reduce excessively high levels of phosphates in the blood (hyperphosphatemia), if it is given together with famotidine.

Famotidine Ranigast and side effects

Like all medicines, Famotidine Ranigast can cause side effects, although not everyone gets them.

If you notice any of the following very rare but serious side effects, stop taking Famotidine Ranigast and contact your doctor immediately see a doctor:

Sudden wheezing, swelling of the lips, tongue and throat or body, rash, redness, fainting or difficulty swallowing (serious allergic reaction).

Red skin with blistering or peeling . It is also possible for large blisters and bleeding to occur around the lips, eyes, mouth, nose and genitals, or for large areas of the skin to peel off. This may be Stevens-Johnson syndrome or toxic epidermal necrolysis.

Yellowing of the skin, dark urine and tiredness, which may be symptoms of liver problems (hepatitis, cholestatic jaundice).

Other side effects include:

Common (affects less than 1 in 10 people):

headache, dizziness;

constipation, diarrhea.

Uncommon (affects less than 1 in 100 people):

anorexia;

taste disturbances;

dry mouth, nausea and/or vomiting, feeling of discomfort or fullness in the abdomen, flatulence;

rash, itching, hives;

fatigue.

Very rare (occur in less than 1 in 10,000 patients):

deficiency of all normal blood cells: red blood cells, white blood cells and platelets;

temporary mental disorders including depression, anxiety , agitation, disorientation, confusion and hallucinations, decreased libido, insomnia;

convulsions, epileptic seizures accompanied by loss of consciousness, convulsions, salivation, trismus, sometimes rapid eye movements (especially in patients with renal impairment) , abnormal feeling, drowsiness;

interstitial pneumonia, sometimes fatal;

impaired liver enzyme activity;

excessive hair loss;

joint pain, muscle cramps;

atrioventricular block, QT prolongation (especially in patients with renal impairment);

impotence;

pressure in the chest.

Rare cases of gynecomastia have been observed in controlled clinical trials, but the incidence was no greater than with placebo.